Pteridines

International Conferences on Pterins and Folates*

1. Paris, France, September 28-30, 1952 (Organized by: M.Polonovski)

2. London, England, UK, March 22-26, 1954 (Organized by: W.Jacobsen and A.Albert)

3. Stuttgart, Germany, September 1962 (Organized by: W.Pfleiderer and E.C.Taylor)

4. Toba, Japan, July 21-25, 1969 (Organized by: K.Nakanishi)

5. Konstanz, Germany, April 14-18, 1975 (Organized by: W.Pfleiderer)

6. La Jolla, California, USA; September 25-28, 1978 (Organized by: G.M.Brown, J.J.Burchall, F.M.Huennekens, R.L.Kisliuk, S.Kaufman, J.A.Montgomery, T.Shiota, J.M.Whiteley)

7. St. Andrews, Scotland, UK, September 21-24, 1982 (Organized by: J.A.Blair, H.Woods)

8. Montreal, Canada, June 15-20, 1986 (Organized by: B.A.Cooper, M.V.Whitehead)

9. Zürich, Switzerland, September 3-8, 1989 (Organized by: H.Ch.Curtius, S.Ghisla, N.Blau)

10. Orange Beach, Alabama, USA, March 21-23, 1993 (Organized by: J.Ayling, G.Nair, C.Baugh)

11. Berchtesgaden, Germany, June 15-20, 1997 (Organized by: W.Pfleiderer, H.Rokos)

12. Bethesda, Maryland, USA, June 17-22, 2001 (Organized by: S.Milstien, G.Kapatos, R.Levine, B.Shane)

13. Egmond aan Zee, The Netherlands, June 20-24, 2005 (Organized by: G.Jansen, G.Peters)

14. Jeju, Korea, June 7-12, 2009 (Organized by: J.Yim, N.Blau)

15. Anatalya, Turkey, May 9-13, 2012 (Organized by: T.Baydar, E.R.Werner, G.Sahin, D.Fuchs)

*Information on meetings 1 to 7 is based on an article by Adrain Albert. How it all began: A brief history of the Pteridine Symposia. In: Cooper BA, Whitehead VM, eds. Chemistry and Biology of Pteridines and Folic Acid Derivatives. Berlin-NewYork: Walter deGruyter 1986; 1-12.

Gowland Hopkins Lectures delivered at International Conferences on Pterins & Folates

This lecture is awarded to eminent researchers in the field of pteridines and folates and is held in memory of Sir Frederick Gowland Hopkins (1861-1947), who won the Noble Price for Physiology and Medicine in 1929 (with Christiaan Eijkman) for the discovery of vitamins. Hopkins did also pioneering work in pteridine research, including the first description of the yellow butterfly pigments (Nature (London) 1889;40:335).

1982
Frank M. Huennekens (Scripps Clinic and Research Foundation, La Jolla, CA, USA)
"Transport of folate and pterin compounds"

1986
Stephen J. Benkovic (The Pennsylvania State University, University Park, PA, USA)
"The mechanism of action of folate and pterin requiring enzymes"

1989
Gene M.Brown (Massachusetts Institute of Technology, Cambridge, MA, USA)
"Biosynthesis of tetrahydrobiopterin and related compounds"

1993
Wolfgang Pfleiderer (Universität Konstanz, Konstanz, Germany)
"Natural pteridines - a chemical hobby"
Edward C. Taylor (Princeton University, Princeton, NJ, USA)
"Design and synthesis of inhibitors of folate-dependent enzymes as antitumor agents"

1997
John M. Scott (Trinity College Dublin, Dublin, Ireland)
"Folate and the prevention of disease"

2001
Rowena G. Matthews (University of Michigan, Ann Arbor, MI, USA)
"Making methionine: a love affair with folate"

2005
Nenad Blau (Universität Zürich, Zürich, Schweiz)
"Molecular and metabolic bases of phenylketonuria and tetrahydrobiopterin deficiencies"
Barry Shane (University of California, Berkeley, CA, USA)
"Molecular genetic models for investigating the regulation of one-carbon metabolism"

2009
Gregory Kapatos (Wayne State University School of Medicine, Detroit, MI, USA)
"The ups and downs of GTP cyclohydrolase I: a neuroscience point of view"
Dean Appling (University of Texas, at Austin, Austin, TX, USA)
“Enzymology of mammalian mitochondrial one-carbon metabolism”

2012

Ernst R. Werner (Innsbruck Medical University, Innsbruck Austria)
“Three classes of tetrahydrobiopterin-dependent enzymes”